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View our 2006 Accomplishment Report [pdf]
While Accelerate Brain Cancer Cure is a recent arrival to the brain cancer field, the organization's focused research efforts are yielding promising results and measurable impact.
Accelerate Brain Cancer Cure's 2001-2006 Project Awards By Area of Study
- To date, Accelerate Brain Cancer Cure has awarded more than $5.2M to highly qualified research investigators and physicians-scientists from 22 institutions. The award money has funded 54 Project Awards, 3 Young Investigator Awards and 1 Fellowship Award. Accelerate Brain Cancer Cure has leveraged its resources and procured additional funding for three of the Project Awards by joining forces in collaborative research efforts with the National Brain Tumor Foundation, the Pediatric Brain Tumor Foundation, and the Tug McGraw Foundation.
- Through Project and Young Investigator Awards, Accelerate Brain Cancer Cure resources have been deployed to advance translational research across a broad range of promising treatment strategies for brain cancer, including the following areas:
- optimizing the effectiveness of novel "targeted therapies" (i.e., agents designed to primarily disable cancer cells while leaving normal brain cells untouched) as single-agent therapies or in combination with other drugs and treatments modalities;
- engineering vaccines and antibodies against cancer-specific proteins to treat and prevent tumor recurrence;
- identifying genetic variations that influence tumor response to therapy useful for treatment decisions and drug development;
- developing biochemical and technological interventions that overcome the natural vascular barrier that severely limits entry of the vast majority of drug molecules from the systemic circulation into the brain; and
- developing tumor imaging and other non-invasive technologies into robust tools, reliably predicting tumor responsiveness and for monitoring disease progression.
- To date, Accelerate Brain Cancer Cure researchers have published over 75 articles and abstracts of their findings and made significant contributions to the field. One of the most influential contributions to the field is a November 2005 publication by ACCELERATE BRAIN CANCER CURE awardee Dr. Paul Mischel in the prestigious New England Journal of Medicine. Dr. Mischel's work is a critical breakthrough and brings the field a significant step closer to rationally designing treatment for individual brain cancer patients.
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